This project seeks to organize, develop the infrastructure, and support the creation of a transdisciplinary team of Black researchers and supporting allies. The goal is to advance synergies in social-structural health research to accelerate the development of strategies to eliminate Black health disparities.This project will open discussion channels among Black-led organizations, health service users, and researchers who will receive direction on their work and increase their capacity to collaboratively address health research priorities with Black communities. The results will lead to the development of a research agenda to support the reduction and elimination of Black health disparities through interdisciplinary collaboration between Black university-based researchers and Black community leaders. The agenda will guide evidence based research, policy decisions, and priorities for Black communities. The project will produce a model for best practices for Black community-led research interventions and models of Black community-academic partnerships.